The replication characteristics of infectious laryngotracheitis virus ( ILTV ) in the respiratory and conjunctival mucosa
نویسندگان
چکیده
The replication characteristics of infectious laryngotracheitis virus (ILTV) in the respiratory and conjunctival mucosa Vishwanatha R.A.P. Reddy, Lennert Steukers, Yewei Li, Walter Fuchs, Alain Vanderplasschen & Hans J. Nauwynck a Faculty of Veterinary Medicine, Laboratory of Virology, Department of Virology, Parasitology and Immunology, Ghent University, Merelbeke, Belgium b Institute of Molecular Biology, Friedrich-Loeffler-Institut, Federal Research Institute for Animal Health, Greifswald, Germany c Laboratory of Immunology-Vaccinology (B43b), Department of infectious and parasitic diseases, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium Accepted author version posted online: 21 Aug 2014.
منابع مشابه
Replication Kinetic of Infectious Laryngotracheitis Virus in Embryonic Chicken Neural Stem Cell
Background and Aims: Infectious laryngotracheitis virus (ILTV) infection causes a highly contagious respiratory disease in poultry leads to significant economic losses in the poultry industry. The genomic and antigenic characteristics between virulent and vaccine strains of ILTV are very similar. The ability of embryonated chicken neural stem (CNS) cell for differential diagnosis of ILTV strain...
متن کاملProtection Induced in Broiler Chickens following Drinking-Water Delivery of Live Infectious Laryngotracheitis Vaccines against Subsequent Challenge with Recombinant Field Virus
Infectious laryngotracheitis virus (ILTV) causes acute upper respiratory tract disease in chickens. Attenuated live ILTV vaccines are often used to help control disease, but these vaccines have well documented limitations, including retention of residual virulence, incomplete protection, transmission of vaccine virus to unvaccinated birds and reversion to high levels of virulence following bird...
متن کاملThe non-essential UL50 gene of avian infectious laryngotracheitis virus encodes a functional dUTPase which is not a virulence factor.
The DNA sequence of the infectious laryngotracheitis virus (ILTV) UL50, UL51 and UL52 gene homologues was determined. Although the deduced UL50 protein lacks the first of five conserved domains of the corresponding proteins of mammalian alphaherpesviruses, the ILTV gene product was also shown to possess dUTPase activity. The generation of UL50-negative ILTV mutants was facilitated by recombinat...
متن کاملThe UL47 gene of avian infectious laryngotracheitis virus is not essential for in vitro replication but is relevant for virulence in chickens.
The genome of infectious laryngotracheitis virus (ILTV) exhibits several differences from those of other avian and mammalian alphaherpesviruses. One of them is the translocation of the conserved UL47 gene from the unique long (UL) to the unique short (US) genome region, where UL47 is inserted upstream of the US4 gene homologue. As in other alphaherpesviruses, UL47 encodes a major tegument prote...
متن کاملDetection of infectious laryngotracheitis virus (Gallid herpesvirus-1) from clinically infected chickens in Egypt by different diagnostic methods
Infectious laryngotracheitis (ILT) disease is an acute highly contagious viral disease leading to massive economic losses to the national poultry industry. This study aimed to identify the most accurate and rapid diagnostic methods to rescue layer poultry farms from intense outbreaks in Egypt. Fifty pathological specimens were collected and subjected to virus isolation (VI), histopathology, dir...
متن کامل